Corrected sodium for hyperglycemia
- Category: Renal and metabolic
- Version: v1.0.1
- Reviewed: Reviewed 6 Sep 2026
- Validation: Validation pending
Corrected Na = measured Na + (factor ÷ 100) × (glucose − 100), with glucose in mg/dL (mmol/L × 18). No correction is applied at or below 100. Both published factors are shown: Katz 1.6 (1973, theoretical) and Hillier 2.4 (1999, measured in 6 healthy adults).
A corrected lab value read against the ordinary sodium reference frame, so there are no bands. Both factors are adult-derived with no paediatric validation [NEEDS SOURCE for a paediatric factor or DKA-guideline endorsement]. Hillier’s data are non-linear: above ~400 mg/dL the true factor climbs toward ~4.0, so the real corrected sodium may exceed even the 2.4 estimate. Units are the main hazard: glucose must be mg/dL for these coefficients.
References
- Katz MA. Hyperglycemia-induced hyponatremia — calculation of expected serum sodium depression. N Engl J Med. 1973;289(16):843–844.PMID 4763428DOI 10.1056/NEJM197310182891607
- Hillier TA, Abbott RD, Barrett EJ. Hyponatremia: evaluating the correction factor for hyperglycemia. Am J Med. 1999;106(4):399–403.PMID 10225241DOI 10.1016/S0002-9343(99)00055-8
- MDCalc / Scholastica. Sodium Correction for Hyperglycemia. Independent reproduction of both formulas (Katz +0.016·(glucose−100); Hillier +0.024·(glucose−100)) with the 100 mg/dL reference.Source
Reproduction rights
Freely reproducible.Simple published linear correction formulas; the coefficients 1.6/2.4 and the 100 mg/dL reference are facts, not copyrightable expression, and there is no verbatim scale text (corrected-sodium.md §IP status).
Independent clinical validation: pending
Two independent clinical validators will be named here once review is complete.
- 2026-09-03v1.0.0Initial releaseInitial published text.
- 2026-09-06v1.0.1ClarificationAdded a one-line description for the catalogue card. No rule, threshold or reference changed.
Other renal and metabolic scores
- Anion gapAnion gap from electrolytes, with an albumin-corrected value for hypoalbuminaemia
- Corrected calcium for albuminTotal calcium adjusted for serum albumin
- KDIGO AKI stagingAcute kidney injury stage from creatinine and urine output
- Serum osmolality and osmolar gapCalculated osmolality and the osmolar gap, with ethanol accounted for
Important. For use by qualified health professionals as an informational and educational aid. It supports clinical judgment and does not replace it. Verify every result independently before making a clinical decision. This is not a medical device.