PELOD-2 (Pediatric Logistic Organ Dysfunction-2)
- Category: Organ dysfunction
- Version: v1.0.1
- Reviewed: Reviewed 6 Sep 2026
- Validation: Validation pending
PELOD-2 total = the sum of 10 items across 5 organ systems, range 0–33, taking the worst value in the window for each item.
- Neurologic
- Glasgow Coma Scale ≥ 11 → 0, 5–10 → 1, 3–4 → 4; pupils both fixed → 5, both reactive → 0.
- Cardiovascular
- lactate < 5 mmol/L → 0, 5–10.9 → 1, ≥ 11 → 4; mean arterial pressure is scored 0, 2, 3 or 6 against age-banded cutoffs, across six bands (0–<1, 1–11, 12–23, 24–59, 60–143 and ≥ 144 months).
- Renal
- serum creatinine at or above the age-band threshold → 2.
- Respiratory
- PaO₂/FiO₂ ≤ 60 → 2; PaCO₂ ≤ 58 mmHg → 0, 59–94 → 1, ≥ 95 → 3; invasive mechanical ventilation → 3, and mask ventilation does not count.
- Haematologic
- white cell count ≤ 2 ×10⁹/L → 2; platelets ≥ 142 → 0, 77–141 → 1, ≤ 76 → 2 (×10⁹/L).
A second output reports predicted in-hospital mortality = 1/(1 + e^−logit), with logit = −6.61 + 0.47 × total.
Every item is required. Per the source an unmeasured variable is scored normal, so the caller enters a normal value for anything not measured and a partial dataset understates the score. Pupillary reaction is binary here: a unilateral fixed pupil has no published point value [NEEDS SOURCE], only the both-fixed option scores, and unilateral findings need an explicit local rule. The predicted-mortality output is a population-level association from the derivation cohort (France/Belgium, n = 3,671, 6% mortality) and requires recalibration before predictive use elsewhere. No severity bands exist or are shown. That is a settled decision, and the organ-count mortality figures in the paper are context, not a banding. One published-table gap is resolved conservatively: in the 24–59-month band, Table 6 leaves a MAP of exactly 45 mmHg in no printed range. This calculator scores it 3, the higher-severity reading; the public ESPNIC calculator scores it 2. It is the only value at which the two tools disagree. Scope: the derivation excluded premature newborns and patients aged 18 years or older, so 216 months and above is rejected as an exclusive ceiling. PaO₂/FiO₂ is considered normal in cyanotic congenital heart disease. Use the pre-sedation GCS estimate if sedated.
References
- Leteurtre S, Duhamel A, Salleron J, Grandbastien B, Lacroix J, Leclerc F; GFRUP. PELOD-2: an update of the PEdiatric logistic organ dysfunction score. Crit Care Med. 2013;41(7):1761–1773.PMID 23685639DOI 10.1097/CCM.0b013e31828a2bbd
- Leteurtre S, Duhamel A, Deken V, Lacroix J, Leclerc F; GFRUP. Daily estimation of the severity of organ dysfunctions in critically ill children by using the PELOD-2 score. Crit Care. 2015;19:324.PMID 26369662DOI 10.1186/s13054-015-1054-y
Reproduction rights
Freely reproducible.PELOD-2's algorithm, thresholds, coefficients and age bands are non-copyrightable facts; the authors state the score 'will be in the public domain' and may be freely used (Leteurtre 2013, Abstract/Discussion). Item labels (Both reactive/Both fixed, yes/no) are functional. GCS is an external instrument (Teasdale & Jennett) whose response-descriptor wording must be sourced separately if a GCS entry widget is built (pelod2.md IP status).
Independent clinical validation: pending
Two independent clinical validators will be named here once review is complete.
- 2026-09-03v1.0.0Initial releaseInitial published text.
- 2026-09-06v1.0.1ClarificationAdded a one-line description for the catalogue card. No rule, threshold or reference changed.
Other organ dysfunction scores
Important. For use by qualified health professionals as an informational and educational aid. It supports clinical judgment and does not replace it. Verify every result independently before making a clinical decision. This is not a medical device.