PaO₂/FiO₂ ratio (P/F)
- CategoryRespiratory
- Versionv1.0.0
- Reviewed2026-07-25
- ValidationIndependent clinical validation: pending
P/F ratio = PaO₂ ÷ FiO₂, with PaO₂ in mmHg (kPa is converted using 1 kPa = 7.50062 mmHg) and FiO₂ as a fraction from 0.21 to 1. A single dimensionless value is returned; it is displayed rounded to a whole number, but the interpretation bands are matched against the unrounded ratio. Bands follow the Berlin (2012) adult ARDS severity strata: ≤ 100 severe, > 100 to ≤ 200 moderate, > 200 to ≤ 300 mild, and > 300 above the ARDS oxygenation threshold.
The Berlin bands are validated in adults and require PEEP/CPAP ≥ 5 cm H₂O. In children, PALICC-2 grades invasive-ventilation severity by oxygenation index (OI/OSI) rather than P/F, and uses P/F on non-invasive support. Berlin mortality figures are population associations, not individual predictions.
| Result | Interpretation |
|---|---|
| ≤ 100 | ≤ 100 — Corresponds to the severe category in the Berlin ARDS definition (with PEEP or CPAP ≥ 5 cm H₂O). |
| >100 to 200 | > 100 to ≤ 200 — Corresponds to the moderate category in the Berlin ARDS definition (with PEEP or CPAP ≥ 5 cm H₂O). |
| >200 to 300 | > 200 to ≤ 300 — Corresponds to the mild category in the Berlin ARDS definition (with PEEP or CPAP ≥ 5 cm H₂O). |
| > 300 | > 300 — Above the Berlin ARDS oxygenation threshold. Interpret in the full clinical context. |
References
- ARDS Definition Task Force; Ranieri VM, et al. Acute respiratory distress syndrome: the Berlin Definition. JAMA. 2012;307(23):2526–2533.PMID 22797452DOI 10.1001/jama.2012.5669
- Emeriaud G, et al. Executive Summary of the Second International Guidelines for the Diagnosis and Management of Pediatric ARDS (PALICC-2). Pediatr Crit Care Med. 2023;24(2):143–168.PMID 36661420DOI 10.1097/PCC.0000000000003147
Reproduction rights
Freely reproducible.Arithmetic ratio; Berlin/PALICC-2 numeric thresholds are facts, not copyrightable expression (pf-sf.md IP status).
Independent clinical validation: pending
Two independent clinical validators will be named here once review is complete.
- 2026-07-25v1.0.0Initial releaseInitial release: P/F ratio with Berlin severity bands.