Corrected QT interval (QTc — Bazett & Fridericia)
- CategoryGeneral
- Versionv1.0.0
- Reviewed2026-07-25
- ValidationIndependent clinical validation: pending
Convert the heart rate to the R–R interval in seconds: RR = 60 ÷ HR (if you enter the R–R interval directly it is used as given). Bazett QTc = QT ÷ √RR. Fridericia QTc = QT ÷ RR^(1/3) (the cube root of RR). Both use RR in seconds and return QTc in the same unit as the QT you enter (milliseconds). At a heart rate of 60 (RR = 1 s) both corrections equal the raw QT.
Not a clinical device: a prolonged QTc is a screening flag, not a diagnosis of long QT syndrome (established with full criteria — Schwartz score, symptoms, family history, genetics). Formula choice changes the answer: Bazett over-corrects at fast rates and under-corrects at slow rates, so it systematically over-calls prolongation in children (who run high heart rates); when HR is outside ~60–100 bpm, Fridericia is the more defensible correction. Interpretation bands are applied ONLY to the Bazett QTc, because the pediatric 440/460/480 ms thresholds (Phan 2015; Andršová 2020) were derived with Bazett and the research states they are not equivalent for a Fridericia QTc; the Fridericia value is reported without bands. Adult sex-specific cutoffs (Goldenberg 2006) must not be applied to children. QTc is only as good as the QT measurement (lead, tangent method, U-wave exclusion, machine vs manual). [NEEDS SOURCE]: an authoritative pediatric QT/HR reference-interval table — the QT (~200–700 ms) and HR (~30–250 bpm) input bounds here are engineering sanity guards, not values from a fetched normative table. [NEEDS SOURCE]: the exact Goldenberg 2006 age/sex-binned millisecond boundaries could not be retrieved from an open full-text source.
| Result | Interpretation |
|---|---|
| ≤ 440 | ≤ 440 ms — At or below the pediatric upper limit of normal for a Bazett-corrected QTc (Andršová 2020; Phan 2015). |
| >440 to 460 | > 440 to ≤ 460 ms — Borderline zone between the pediatric upper limit of normal (~440 ms) and the prolonged threshold (460 ms) for a Bazett QTc (Andršová 2020; Phan 2015). |
| >460 to <480 | > 460 to < 480 ms — Above the pediatric prolonged-QTc threshold of 460 ms for a Bazett QTc (Phan 2015 endorsed 460 ms in infants/young children; Andršová 2020). |
| ≥ 480 | ≥ 480 ms — At or above the level Andršová 2020 cite as diagnostic of long QT syndrome for a Bazett QTc. QTc alone is not diagnostic — LQTS is established with full criteria (Schwartz score, symptoms, family history, genetics). |
References
- Bazett HC. An analysis of the time-relations of electrocardiograms. Heart. 1920;7:353–370. Reprinted Ann Noninvasive Electrocardiol. 1997;2(2):177–194.DOI 10.1111/j.1542-474X.1997.tb00325.x
- Fridericia LS. Die Systolendauer im Elektrokardiogramm bei normalen Menschen und bei Herzkranken. Acta Med Scand. 1920;53:469–486. English translation Ann Noninvasive Electrocardiol. 2003;8(4):343–351.DOI 10.1111/j.0954-6820.1920.tb18266.x
- Phan DQ, Silka MJ, Lan Y-T, Chang R-KR. Comparison of formulas for calculation of the corrected QT interval in infants and young children. J Pediatr. 2015;166(4):960–964.PMID 25648293DOI 10.1016/j.jpeds.2014.12.037
- Andršová I, Hnatkova K, Helánová K, et al. Problems with Bazett QTc correction in paediatric screening of prolonged QTc interval. BMC Pediatr. 2020;20:558.PMID 33317470DOI 10.1186/s12887-020-02460-8
- Goldenberg I, Moss AJ, Zareba W. QT interval: how to measure it and what is "normal." J Cardiovasc Electrophysiol. 2006;17(3):333–336.PMID 16643414DOI 10.1111/j.1540-8167.2006.00408.x
Reproduction rights
Freely reproducible.Both corrections are mathematical formulas (√RR and RR^(1/3) normalizations) and the pediatric thresholds (440/460/480 ms) are numeric facts from the literature — neither is copyrightable (qtc.md IP status).
Independent clinical validation: pending
Two independent clinical validators will be named here once review is complete.
- 2026-07-25v1.0.0Initial releaseInitial release: QTc by Bazett and Fridericia with pediatric Bazett-based prolongation bands.